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Vitamins and Coenzymes

Vitamins and Coenzymes
Acyl carrier protein (ACP) plays an important role in the biosynthesis of

amino acids
sugars
carbohydrates
fatty acids

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Vitamins and Coenzymes
The disease Beriberi is due to a dietary deficiency in

vitamin B12
vitamin B1 (thiamine)
vitamin B2 (riboflavin)
vitamin B6 (pyridoxine)

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Vitamins and Coenzymes
The occurrence of metals such as iron or molybdenum in some flavoproteins can

form chelation
stabilize the semiquinone
de-stabilize the semiquinone
all of these

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Vitamins and Coenzymes
A deficiency of Vitamin K results in a decreased level of

fibrinogen
prothrombin
fibrin
thrombin

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Vitamins and Coenzymes
An enzyme, L-folate reductase reduces folic acid to

dihydrofolic acid
hydrofolic acid
trihydrofolic acid
tetrahydrofolic acid

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Vitamins and Coenzymes
The reductant, NADH, transfers the electrons via a flavo-proteins to the specific disulfide (S-S) protein to form a dithiol (SH,SH) protein which converts vitamin

B12(Co2+)to B12(Co)
B12(Co+)to B12(Co2+)
B12(Co) to B12(Co2+)
B12(Co2+)to B12(Co+)

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